DEFINITION

Coptis Species Rhizome Powder consists of the dried rhizome of Coptis chinensis Franch., Coptis deltoidea C.Y.Cheng & P.K.Hsiao, or Coptis teeta Wall. (Fam. Ranunculaceae) with roots removed and reduced to a fine or very fine powder. It contains NLT 9.0% and NMT 18% of total quaternary protoberberine alkaloids calculated on the dried basis as the sum of columbamine (C₂₀H₂₀NO₄⁺), jatrorrhizine (C₂₀H₂₀NO₄⁺), epiberberine (C₂₀H₁₈NO₄⁺), coptisine (C₁₉H₁₄NO₄⁺), palmatine (C₂₁H₂₂NO₄⁺), and berberine (C₂₀H₁₈NO₄⁺); and NLT 5.0% and NMT 12% of berberine on the dried basis.

POTENTIAL CONFOUNDING MATERIALS...