Vitex negundo Leaf Dry Extract

Vitex negundo Leaf Dry Extract

DEFINITION

Vitex negundo Leaf Dry Extract consists of the dried leaves of Vitex negundo L. (Fam. Lamiaceae), commonly known as Chinese Chaste Tree or Five-Leaf Chaste Tree, by extraction with hydroalcoholic mixture. It contains NLT 2.5% of iridoid glycosides, calculated as the sum of agnuside and negundoside on the dried basis.

POTENTIAL CONFOUNDING MATERIALS

Vitex agnus-castus L.

Vitex rotundifolia L.f

Vitex trifolia L.

CONSTITUENTS OF INTEREST

Iridoid glycosides: Negundoside, nishindaside, and agnuside

IDENTIFICATION

• A. Thin-Layer Chromatography

Standard solution A: 3 mg/mL each of USP Negundoside RS...